glycine tablets 100 mg

Introduction to High-Quality Glycine Solutions Glycine, the simplest amino acid, plays a pivotal role across a multitude of industries due to its unique chemical properties and biological functions. As a fundamental building block for proteins and a precursor for various metabolic compounds, its applications span from pharmaceuticals and food & beverage to animal nutrition and agrochemicals. The demand for high-purity glycine for sale is consistently growing, driven by advancements in biotechnology, increasing global population, and stringent quality requirements in critical sectors. This comprehensive guide provides an in-depth analysis of the technical aspects, market trends, and practical applications of industrial-grade glycine, catering to B2B decision-makers and technical professionals seeking reliable and high-performance solutions. Our commitment to delivering superior quality glycine ensures that our products meet the exacting standards of diverse industrial applications, providing significant value through consistent purity, optimal functionality, and robust supply chain reliability. Whether for advanced pharmaceutical synthesis or as a critical nutrient in animal feed, understanding the intricate details of glycine production, its technical specifications, and its varied uses is essential for informed procurement decisions. Industry Trends and Market Dynamics for Glycine The global market for glycine is experiencing steady growth, propelled by its expanding utility in key sectors. According to recent market analyses, the global glycine market size was valued at approximately USD 6.5 billion in 2022 and is projected to reach USD 9.8 billion by 2030, exhibiting a compound annual growth rate (CAGR) of around 5.2% during the forecast period. This growth is predominantly driven by: Pharmaceutical Sector Expansion: Glycine is crucial as an active pharmaceutical ingredient (API) in certain medications, an excipient, and an intermediate in drug synthesis. The rise in chronic diseases and pharmaceutical research fuels this demand. Growth in Food & Beverage Industry: Used as a flavor enhancer, stabilizer, preservative, and nutritional supplement, especially in functional foods and beverages. Consumer preference for natural ingredients also boosts demand for high-purity glycine. Animal Feed Additives: Glycine is increasingly utilized in animal nutrition to improve feed efficiency, promote growth, and enhance animal health, particularly in poultry and swine industries. Sustainable Agricultural Practices: Its application in agrochemicals, such as herbicides and pesticides, continues to be a significant market segment. Cosmetics and Personal Care: As a moisturizing agent and pH regulator, glycine finds niche applications in the personal care industry. Regionally, Asia-Pacific remains the largest market due to robust manufacturing bases and high consumption rates in China and India, followed by North America and Europe. The competitive landscape is characterized by a mix of large-scale chemical producers and specialized glycine manufacturers, focusing on product innovation and adherence to stringent quality standards to differentiate their offerings for glycine for sale . Detailed Glycine Manufacturing Process Flow The production of high-purity glycine involves sophisticated chemical synthesis and rigorous purification stages to ensure the final product meets exacting industry standards. While several methods exist, the ammonolysis of chloroacetic acid and the Strecker synthesis are the most common industrial routes. Our facilities primarily utilize advanced variants of these processes, optimized for efficiency, purity, and environmental responsibility. Process Overview (Ammonolysis of Chloroacetic Acid): Raw Materials Sourcing: High-grade chloroacetic acid and ammonia (in aqueous solution) are procured. These are critical precursors, and their purity directly impacts the final glycine quality. Reaction/Synthesis: Chloroacetic acid reacts with an excess of ammonia under controlled temperature and pressure conditions. This nucleophilic substitution reaction yields glycine and ammonium chloride. The reaction vessel is carefully monitored to optimize conversion rates and minimize side reactions. Schematic Step: R-Cl + NH 3 → R-NH 2 + HCl (where R-Cl is chloroacetic acid derivative) Neutralization and pH Adjustment: The reaction mixture, containing glycine and ammonium chloride, undergoes pH adjustment to facilitate the separation of glycine. The pH is carefully controlled to precipitate glycine. Purification and Crystallization: Crude glycine is separated from the ammonium chloride mother liquor. Multiple crystallization steps (e.g., cooling crystallization or evaporative crystallization) are employed to achieve high purity. This stage is critical for removing impurities, including heavy metals, other amino acids, and unreacted raw materials. Washing and Filtration: The crystallized glycine is thoroughly washed with deionized water to remove residual impurities and then filtered to separate the solid product from the liquid phase. Drying: The wet glycine crystals are dried using specialized dryers (e.g., vacuum dryers or fluid bed dryers) to achieve the desired moisture content. Careful control of drying parameters prevents degradation and ensures consistent particle size. Milling and Sieving: Depending on the required particle size for specific applications, the dried glycine may be milled and sieved to produce uniform particle distribution. Quality Control and Packaging: Every batch undergoes rigorous testing to ensure compliance with international standards (e.g., USP, FCC, EP, JP, ISO). Approved batches are then packaged in multi-layer bags or drums, designed for optimal stability and shelf life, ready for glycine sale . Our manufacturing processes emphasize energy efficiency, waste minimization, and robust environmental controls. We adhere to ISO 9001 quality management systems and ISO 14001 environmental management standards, ensuring not only product excellence but also sustainable operational practices. The process is continually optimized for consistent yield, purity, and safety, resulting in a premium glycine for sale product. Figure 1: High-purity crystalline glycine ready for packaging. Technical Specifications of High-Quality Glycine Understanding the precise technical specifications is paramount for procurement professionals and R&D teams. Our glycine products are meticulously tested against international pharmacopoeia and food chemical codex standards to ensure unparalleled quality and performance across various grades. Below is a detailed specification table for our premium-grade glycine, which is often sought after for specialized applications requiring exceptional purity. Table 1: Technical Specifications of Premium-Grade Glycine Parameter Specification (USP/FCC Grade) Testing Method/Standard Chemical Formula C 2 H 5 NO 2 N/A Molecular Weight 75.07 g/mol N/A Assay (on dried basis) 98.5% ~ 101.5% USP <781> / Titrimetry Clarity of Solution Clear and Colorless Visual Inspection pH (5% solution at 25°C) 5.9 ~ 6.4 USP <791> / pH Meter Loss on Drying ≤ 0.2% USP <731> / Gravimetry Residue on Ignition ≤ 0.1% USP <281> / Gravimetry Heavy Metals (as Pb) ≤ 5 ppm USP <251> / ICP-MS Chloride ≤ 0.007% USP <221> / Turbidimetry Sulfate ≤ 0.006% USP <221> / Turbidimetry Arsenic ≤ 1 ppm USP <211> / AAS Other Amino Acids Not detected HPLC Particle Size (D90) Typically 100-300 µm (customizable) Laser Diffraction Microbial Limits Total Plate Count ≤ 100 cfu/g, E. coli Absent USP <61> & <62> This comprehensive set of parameters ensures that our glycine for sale not only meets but often exceeds the requirements of the most demanding applications, offering reliability and consistent performance. We provide Certificates of Analysis (CoA) with every shipment, detailing the tested parameters and confirming compliance. Diverse Application Scenarios and Functional Benefits The versatility of glycine makes it indispensable across numerous industries. Understanding specific application requirements is crucial for selecting the appropriate glycine types and grades. 1. Pharmaceutical Grade Glycine: API and Excipient: Used in antacids, as a component in intravenous solutions, and as a cryoprotectant for biological samples. Its buffering capacity makes it valuable in pharmaceutical formulations. Drug Synthesis Intermediate: A precursor for various heterocyclic compounds, peptides, and other pharmaceutical intermediates. Diagnostic Reagents: Employed in various diagnostic kits and biochemical assays due to its non-interfering properties. Benefits: High purity, low endotoxin levels, consistent solubility, and compliance with USP, EP, and JP pharmacopoeias are critical. 2. Food Grade Glycine: Flavor Enhancer: Imparts a sweet taste and enhances the umami flavor in various food products, particularly in processed meats, sauces, and instant foods. Preservative and Antioxidant: Can inhibit bacterial growth and act as an antioxidant in certain food systems, extending shelf life. Sweetener Synergist: Used in conjunction with other sweeteners to reduce aftertastes and create a more balanced flavor profile. Nutritional Supplement: Included in functional foods and dietary supplements for its role in metabolism. Benefits: FCC compliance, high solubility, neutral pH, and safety for human consumption. 3. Feed Grade Glycine: Animal Nutrition: An essential amino acid for poultry, swine, and aquaculture. It supports growth, feathering, and overall metabolic health. Precursor for Creatine Synthesis: Important for energy metabolism in animals. Digestibility Enhancer: Improves nutrient utilization in feed formulations. Benefits: High bioavailability, consistent purity, and cost-effectiveness for wholesale glycine powder . 4. Industrial and Cosmetic Applications: Agrochemicals: A key raw material in the synthesis of glyphosate, a widely used herbicide. Chemical Intermediates: Utilized in the synthesis of various specialty chemicals and polymers. Cosmetics: Found in skincare products as a humectant and buffering agent, contributing to skin hydration and pH balance. Benefits: Consistent quality and reliable supply for large-scale industrial use. Our technical team possesses deep expertise in these diverse applications, offering guidance on product selection and optimal usage to maximize the benefits of glycine in your specific processes. Technical Advantages and Quality Assurance Our commitment to excellence is reflected in the technical advantages inherent in our glycine products and the stringent quality assurance protocols that govern our operations. We stand out as a preferred supplier of glycine for sale due to: Unmatched Purity and Consistency: Through advanced synthesis and multi-stage purification, we achieve glycine purity levels often exceeding 99.5%, with minimal impurities. Each batch undergoes thorough analysis to guarantee consistency, critical for sensitive applications. Regulatory Compliance: Our products strictly adhere to major international pharmacopoeias (USP, EP, JP) and food chemical standards (FCC). Our manufacturing facilities are cGMP (current Good Manufacturing Practices) compliant, ensuring the highest standards of production for pharmaceutical and food-grade glycine. Optimized Particle Size Distribution: We offer various particle size specifications, including fine powders and granular forms, tailored to client needs for enhanced solubility, flowability, and blending characteristics in end-user formulations. Robust Supply Chain & Sourcing: Our integrated supply chain management ensures reliable access to high-quality raw materials and efficient, on-time delivery globally. We mitigate supply risks, offering stability for large-volume requirements and wholesale glycine powder purchases. Environmental Responsibility: Our processes are designed to minimize environmental impact, employing sustainable practices in raw material sourcing, waste management, and energy consumption. We hold ISO 14001 certification, demonstrating our commitment to environmental stewardship. Comprehensive Technical Support: Our team of chemical engineers and technical specialists provides expert consultation, assisting clients with product integration, troubleshooting, and optimization of their formulations. These advantages translate into superior performance, reduced risk, and increased efficiency for our clients, solidifying our reputation as a trusted partner in the chemical industry. Vendor Comparison: Selecting the Right Glycine Supplier When evaluating suppliers for glycine sale , critical factors extend beyond just price. A comprehensive assessment of capabilities, certifications, and service offerings is essential for long-term partnership success. Here's a comparison framework to aid your decision-making: Table 2: Key Vendor Comparison Factors for Glycine Procurement Factor Our Offering Typical Market Offering Purity & Consistency ≥ 99.5% guaranteed, batch-to-batch consistency with detailed CoA. Rigorous QC at every stage. Varies widely; often 98-99% with less stringent impurity control. Certifications & Compliance ISO 9001, ISO 14001, cGMP, HACCP, FSSC 22000, Kosher, Halal. Full pharmacopoeial compliance (USP, EP, JP, FCC). May only have basic ISO; cGMP/pharmacopoeial compliance less common for all grades. Traceability & Transparency Complete raw material to finished product traceability. Open documentation. Limited traceability, especially from brokers or smaller suppliers. Customization Options Tailored particle size, specific grades, custom packaging, blend formulations. Standard product offerings; limited flexibility for specific needs. Technical Support Dedicated technical team for application support, problem-solving, and formulation guidance. Basic sales support; technical expertise may be outsourced or limited. Supply Chain Reliability Global distribution network, robust inventory management, risk mitigation strategies. May experience stockouts, longer lead times, less resilient to disruptions. Pricing & Value Competitive pricing reflecting superior quality, consistency, and comprehensive support. Excellent long-term value. Lower initial price often compromises quality, reliability, and support, leading to higher hidden costs. Choosing a supplier is a strategic decision. Our decades of experience and adherence to the highest standards position us as a reliable partner for your glycine requirements, offering not just a product but a complete solution. Customized Glycine Solutions Recognizing that standard products may not always perfectly align with unique industrial requirements, we offer comprehensive customized solutions for glycine for sale . Our flexibility and advanced manufacturing capabilities enable us to tailor our offerings to your precise specifications, optimizing performance and integration into your existing processes. Our Customization Capabilities Include: Particle Size Engineering: We can provide glycine with specific particle size distributions (e.g., fine powder for rapid dissolution, granular for excellent flowability and dust reduction) to meet the requirements of your formulation or process equipment. Tailored Purity Grades: While our standard offerings are of high purity, we can work with clients requiring even tighter specifications for critical trace impurities or specific analytical profiles. Custom Packaging Options: From specialized bulk container111s (e.g., super sacks, jumbo bags) to specific weight packaging for ease of handling or automated lines, we can accommodate diverse packaging needs to optimize your logistics and operations. Custom Blends and Formulations: For clients requiring a pre-mixed blend of glycine with other compatible ingredients, our R&D team can develop custom formulations to streamline your manufacturing process. Regulatory Support for Novel Applications: Our regulatory experts can assist with documentation and compliance for novel applications or specific market registrations, ensuring your products meet local and international standards. By collaborating closely with our clients, we transform specific needs into tangible, high-quality glycine solutions that provide a distinct competitive advantage. Our goal is to be more than a supplier; we aim to be an extension of your R&D and manufacturing capabilities. Application Case Studies Real-world examples demonstrate the tangible benefits of our high-quality glycine in diverse industrial settings. Case Study 1: Enhanced Stability in Pharmaceutical Injectables Client: A leading global pharmaceutical company specializing in injectable medications. Challenge: The client faced issues with API degradation and pH instability in a new injectable formulation, leading to reduced shelf life and regulatory concerns. Existing glycine suppliers could not consistently meet the stringent purity and buffering capacity required. Solution: We provided a customized pharmaceutical-grade glycine, manufactured with exceptionally low impurity profiles and precise pH control. Our technical team collaborated with the client’s R&D to optimize the glycine concentration and particle size for faster dissolution and uniform dispersion. Outcome: The new formulation demonstrated significantly improved stability, extending the product's shelf life by 18 months beyond initial projections. Regulatory approval was swiftly obtained, and the client achieved substantial cost savings by reducing batch rejections and enhancing product efficacy. Our product was crucial in securing market entry for their innovative drug. Case Study 2: Optimizing Animal Feed Efficiency for Poultry Client: A large-scale animal feed producer in Southeast Asia. Challenge: The client was looking to enhance the growth rates and feed conversion ratios (FCR) in their broiler chicken feed formulations while managing production costs for wholesale glycine powder . Inconsistent glycine quality from previous suppliers led to variable performance. Solution: We supplied a high-purity feed-grade glycine with a consistent particle size, ensuring even distribution throughout the feed mix. Our technical experts provided formulation guidance, demonstrating how optimal glycine inclusion could synergize with other amino acids to improve protein utilization. Outcome: The client observed a notable improvement in FCR by 3-5% and increased average daily weight gain in their broiler flocks. This translated to significant operational savings and higher profitability. The consistent quality of our glycine also streamlined their mixing process, reducing production variability. Frequently Asked Questions (FAQ) about Glycine Q1: What are the primary glycine types you offer? A1: We primarily offer Pharmaceutical Grade (USP/EP/JP), Food Grade (FCC), and Feed Grade glycine. Each grade meets specific industry standards and purity requirements for its intended application. We also provide industrial grades for various chemical synthesis purposes. Q2: How should glycine be stored? A2: Glycine should be stored in a cool, dry place, away from direct sunlight and moisture, in tightly sealed original container111s. Recommended storage temperatures are typically between 15°C and 30°C. Proper storage ensures its stability and prevents caking or degradation. Q3: What certifications do your glycine products hold? A3: Our products are manufactured under strict quality systems and hold various certifications including ISO 9001, ISO 14001, cGMP, HACCP, FSSC 22000, Kosher, and Halal. Specific certificates can be provided upon request for glycine for sale . Q4: What is the typical shelf life of your glycine? A4: When stored under recommended conditions, our glycine typically has a shelf life of 2 to 3 years from the date of manufacture. Detailed expiration dates are provided on the product packaging and Certificate of Analysis. Q5: Can you provide samples for R&D purposes? A5: Yes, we encourage potential clients to test our products. Samples of various glycine grades can be provided for R&D and quality evaluation purposes. Please contact our sales team to arrange a sample request. Logistics, Warranty, and Customer Support We understand that reliable logistics, clear warranty terms, and responsive customer support are as crucial as product quality for our B2B partners. Our commitment extends to providing a seamless experience from inquiry to after-sales service for every glycine sale . Lead Time & Fulfillment: Standard Orders: For in-stock standard grades, typical lead times range from 7-14 business days, depending on destination and order volume. Bulk & Wholesale Glycine Powder Orders: For large volume or wholesale glycine powder orders, we establish a customized fulfillment schedule, often with buffer stock arrangements, to ensure continuous supply. Customized Solutions: Lead times for custom formulations or specialized particle sizes will be quoted based on complexity and production schedule, typically 3-6 weeks after specification finalization. Global Logistics: We leverage a robust global logistics network, offering various shipping options (sea, air, rail) to optimize cost and delivery speed, managed by experienced logistics professionals. Warranty & Quality Assurance: Product Quality Guarantee: All our glycine products are guaranteed to meet the specifications detailed in their respective Certificates of Analysis (CoA) and adhere to agreed-upon industry standards (e.g., USP, FCC, EP, JP). Batch Traceability: Every batch is fully traceable from raw material sourcing through production to final delivery, ensuring accountability and facilitating rapid response in case of any issues. Defect Resolution: In the rare event of a product quality issue that deviates from agreed specifications, we commit to swift investigation, root cause analysis, and appropriate resolution, including replacement or credit, in accordance with our quality policy. Customer Support & Technical Assistance: Dedicated Account Managers: Each client is assigned a dedicated account manager to ensure personalized service and efficient communication. Technical Support Team: Our team of highly qualified technical experts is available to provide in-depth support for product application, troubleshooting, formulation advice, and regulatory guidance. 24/7 Online Support: For urgent inquiries, our online support channels are available to provide timely assistance and information. Our aim is to build long-standing relationships based on trust, quality, and mutual success. We stand by our products and our service, ensuring that your procurement of glycine is reliable and beneficial. Conclusion The demand for high-quality glycine for sale continues to grow, driven by its critical role across pharmaceuticals, food & beverage, animal nutrition, and various industrial applications. As a leading manufacturer and supplier, we are dedicated to providing superior glycine products that meet the highest international standards for purity, consistency, and efficacy. Through advanced manufacturing processes, rigorous quality control, and a customer-centric approach, we ensure that our partners receive not just a chemical, but a comprehensive solution backed by expert technical support, reliable logistics, and unwavering commitment to quality. Partner with us to leverage the full potential of high-performance glycine for your innovations and operational success. Explore our offerings and discover how our expertise can add value to your supply chain. References "U.S. Pharmacopeia (USP) - National Formulary (NF)". United States Pharmacopeial Convention. "Food Chemicals Codex (FCC)". United States Pharmacopeial Convention. "European Pharmacopoeia (EP)". European Directorate for the Quality of Medicines & HealthCare (EDQM). "Glycine Market Size, Share & Trends Analysis Report By Grade (Food, Pharma), By Application (Food & Beverages, Pharmaceuticals), By Region (North America, Europe, Asia Pacific), And Segment Forecasts, 2023 - 2030." Grand View Research. "Guidance for Industry: cGMP for Active Pharmaceutical Ingredients." U.S. Food and Drug Administration (FDA).